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4 research outputs found
Trends in the characteristics, dose-limiting toxicities and efficacy of phase I oncology trials: The Cancer Research UK experience.
Author
Claire Barton
Gary Acton
+9 more
Han Hsi Wong
Helen Turner
Jane Peters
Janette McQuillan
Rachel Darby-Dowman
Robert McLeod
Sarah E. R. Halford
Susan Wan
Zoe Backholer
Publication venue
'American Society of Clinical Oncology (ASCO)'
Publication date
Field of study
No full text
Crossref
Erratum: Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer
Author
Alan Boddy
Daniel Rea
+15 more
David Jamieson
Gary Acton
Geoff Hall
Gordon Jayson
James Murray
Jonathan Ledermann
Julieann Sludden
Martin Highley
Nicola Curtin
Raffaella Mangano
Ros Glasspool
Ruth Plummer
Sarah Halford
Yvette Drew
Zoe Backholer
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
A first-in-human study of the dual ROCK I/II inhibitor, AT13148, in patients with advanced cancers.
Author
Dionysios Papadatos-Pastos
Florence I. Raynaud
+12 more
Gavin Halbert
Johann Sebastian De Bono
Karen E Swales
Michelle D Garrett
Paul Jones
Rajiv Kumar
Robert McLeod
Ruth Ruddle
Shaun Decordova
Timothy Anthony Yap
Udai Banerji
Zoe Backholer
Publication venue
'American Society of Clinical Oncology (ASCO)'
Publication date
Field of study
No full text
Crossref
First-in-human, first-in-class phase 1 study of a novel oral multi-AGC kinase inhibitor AT13148 in patients (pts) with advanced solid tumors.
Author
Alan D. Smith
Christine Tran
+14 more
Florence I. Raynaud
Joaquin Mateo
Karen E Swales
Khurum Hayat Khan
Michelle D Garrett
Paul Jones
Rajiv Kumar
Robert McLeod
Ruth Ruddle
Satyanarayana Seeramreddi
Shaun Decordova
Timothy Anthony Yap
Udai Banerji
Zoe Backholer
Publication venue
'American Society of Clinical Oncology (ASCO)'
Publication date
Field of study
No full text
Crossref